Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
There are several matches for 'protease II'.
Please select one from the list below and press Continue to proceed.
<- Back
Continue ->
1286 matches
showing page 1 of 65
•
first
•
previous
•
next
•
last
organism
protein
1)
Escherichia coli K12
ptrB -
Protease
II
; Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues; Belongs to the peptidase S9A family.
[a.k.a. b1845, AAC74915.1, eco:b1845,
Protease II
,
protease II
, ...]
2)
Homo sapiens
SPPL2A - Signal peptide peptidase-like 2A; Intramembrane-cleaving aspartic
protease
(I-CLiP) that cleaves type
II
membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. Also responsible for the intramembrane cleavage of Fas antigen ligand FASLG, which promotes the release of the intracellular FasL domain (FasL ICD). May play a role in the regulation of innate and [...]
[a.k.a. R-HSA-162582, URS0000D6E055, ENST00000558414.1]
3)
Homo sapiens
SPPL3 - Signal peptide peptidase-like 3; Intramembrane-cleaving aspartic
protease
(I-CLiP) that cleaves type
II
membrane protein substrates in or close to their luminal transmembrane domain boundaries. Acts like a sheddase by mediating the proteolytic release and secretion of active site-containing ectodomains of glycan-modifiying glycosidase and glycosyltransferase enzymes such as MGAT5, B4GAT1 and B4GALT1. Catalyzes the intramembrane cleavage of the envelope glycoprotein gp130 and/or the leader peptide gp18LP of the simian foamy virus independent of prior ectodomain shedding by furin or furi [...]
[a.k.a. URS0000EAB286, ENST00000545209.1, Q3MJ04]
4)
Homo sapiens
SPPL2B - Signal peptide peptidase-like 2B; Intramembrane-cleaving aspartic
protease
(I-CLiP) that cleaves type
II
membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity. Catalyzes the intramembrane cleavage of the simian foamy virus processed leader peptide gp18 of the envelope glycoprotein gp130 dependen [...]
[a.k.a. NP_694533.1, ENST00000621568.4, ENSP00000480311]
5)
Homo sapiens
CTSS - Cathepsin S; Thiol
protease
. Key
protease
responsible for the removal of the invariant chain from MHC class
II
molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L.
[a.k.a. 2HH5, 5QC2, 5QC8]
6)
Homo sapiens
SPPL2C - Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic
protease
(I-CLiP) that may be able to cleave type
II
membrane signal peptides in the hydrophobic plane of the membrane.
[a.k.a. ENST00000329196, Q8IUH8, 3.4.23.-]
7)
Homo sapiens
HLA-DQA2 - HLA class
II
histocompatibility antigen, DQ alpha 2 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class
II
molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal
proteases
and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for p [...]
[a.k.a. HLA-DQA1, KY500360, CAM26196.1]
8)
Homo sapiens
HLA-DQB1 - HLA class
II
histocompatibility antigen, DQ beta 1 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class
II
molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal
proteases
and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for pr [...]
[a.k.a. Q30095, ENSP00000308869, UPI000012C0BC]
9)
Homo sapiens
HLA-DRB5 - HLA class
II
histocompatibility antigen, DR beta 5 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class
II
molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal
proteases
and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for pr [...]
[a.k.a. 3127, CAA70524.1, R-HSA-202424]
10)
Homo sapiens
HLA-DRA - HLA class
II
histocompatibility antigen, DR alpha chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class
II
molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal
proteases
and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for pre [...]
[a.k.a. 1T5W, 3122, 2FSE]
11)
Homo sapiens
HLA-DPA1 - HLA class
II
histocompatibility antigen, DP alpha 1 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class
II
molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal
proteases
and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for p [...]
[a.k.a. MH920368, NM_033554, NP_001229453]
12)
Homo sapiens
HLA-DQB2 - HLA class
II
histocompatibility antigen, DQ beta 2 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class
II
molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal
proteases
and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for pr [...]
[a.k.a. DQB2_HUMAN, R-HSA-202424, NP_001185787]
13)
Homo sapiens
HLA-DPB1 - HLA class
II
histocompatibility antigen, DP beta 1 chain; Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class
II
molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal
proteases
and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for pr [...]
[a.k.a. HPA058509, Q95HC1, O98217]
14)
Homo sapiens
ANPEP - Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic
proteases
. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class
II
molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...]
[a.k.a. alanyl aminopeptidase, membrane, PEPN, UPI00022F8740]
15)
Mus musculus
Sppl2a - Signal peptide peptidase-like 2A; Intramembrane-cleaving aspartic
protease
(I-CLiP) that cleaves type
II
membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. Also responsible for the intramembrane cleavage of Fas antigen ligand FASLG, which promotes the release of the intracellular FasL domain (FasL ICD). May play a role in the regulation of innate and [...]
[a.k.a. XM_011239737.2, XM_011239737, 3.4.23.-]
16)
Mus musculus
Sppl3 - Signal peptide peptidase-like 3; Intramembrane-cleaving aspartic
protease
(I-CLiP) that cleaves type
II
membrane protein substrates in or close to their luminal transmembrane domain boundaries. Acts like a sheddase by mediating the proteolytic release and secretion of active site- containing ectodomains of glycan-modifiying glycosidase and glycosyltransferase enzymes such as MGAT5, B4GAT1 and B4GALT1. Plays a role in the regulation of cellular glycosylation processes. Required to link T- cell antigen receptor (TCR) and calcineurin-NFAT signaling cascades in lymphocytes by promoting the [...]
[a.k.a. MGI:1891433, 3.4.23.-, ENSMUST00000150708.1]
17)
Mus musculus
Sppl2b - Signal peptide peptidase-like 2B; Intramembrane-cleaving aspartic
protease
(I-CLiP) that cleaves type
II
membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity; Belongs to the peptidase A22B family.
[a.k.a. XM_006514213, ENSMUST00000035597, ENSMUST00000171471]
18)
Mus musculus
Ctss - Cathepsin S; Thiol
protease
. Key
protease
responsible for the removal of the invariant chain from MHC class
II
molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L; Belongs to the peptidase C1 family.
[a.k.a. R-MMU-1280218, 4BSQ, NM_001267695.2]
19)
Mus musculus
Sppl2c - Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic
protease
(I-CLiP) that may be able to cleave type
II
membrane signal peptides in the hydrophobic plane of the membrane.
[a.k.a. ENSMUSP00000102613, A2A6C4, ENSMUST00000107000.1]
20)
Mus musculus
Anpep - Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic
proteases
. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines (By similarity). May also be involved the cleavage of peptides bound to major histocompatibility complex class
II
molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization (By similarity). May have a role in amino aci [...]
[a.k.a. UPI0000026D96, BC005431, ENSMUST00000206682.1]
1286 matches
showing page 1 of 65
•
first
•
previous
•
next
•
last
<- Back
Continue ->